OSUCCC – James: Year in Review

December 27, 2014 9:02 am
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Test Tubes

2014 Saw New Cancer Hospital & Research Advances at Ohio State For Ohio State’s cancer program, 2014 was a pivotal year that culminated in the opening of the new Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, a 21-story, 306-bed facility that stands as a model for 21st century cancer hospitals. The new James, the third largest cancer hospital in the nation, integrates cancer research, patient...
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Notable Moments in the History of The James Cancer Hospital and Solove Research Institute

December 26, 2014 8:28 am
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Historic James Photo

1947 Following his service in World War II and a fellowship at Memorial Sloan-Kettering Cancer Center, Dr. Arthur G. James returns to his alma mater, The Ohio State University, as assistant professor in the Department of Surgery. Inspired by the cancer care he saw at Memorial Sloan-Kettering, and realizing no cancer centers exist between New York and Texas, he dreams of establishing one in Columbus. 1962 The Columbus Cancer...
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BENEFICIAL FINDINGS: Genetic and Epigenetic Discoveries May Help Improve Cancer Therapies

December 22, 2014 8:39 am
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Dr. Bloomfield

Two genetic and epigenetic studies published in separate journals by OSUCCC – James researchers might improve the treatment of adult acute myeloid leukemia (AML) and other cancers. In one study, researchers developed a scoring system for AML cells that is based on mutations in seven genes and an epigenetic change (DNA methylation) that altered the expression (activity) of the mutated genes. The findings suggest that a score based on...
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ACHILLES ENZYME: A Possible New Target for Brain Cancer Drugs

December 21, 2014 8:15 am
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Robert Baiocchi, MD

A molecule in cells that shuts down the expression of genes might be a promising target for new drugs designed to treat the most frequent and lethal form of brain cancer, according to a new study by researchers at the OSUCCC – James. The findings show that high levels of the enzyme PRMT5 are associated with aggressive growth of the brain cancer glioblastoma multiforme (GBM). GBM is a highly...
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